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         for transfusions in the Emergency Department or even   concern about alloimmunized patients and about the
         to activate massive transfusion protocols can help in the   management of group “O” Negative RBC concentrate to
         rational use of blood . According to Alimohammadi, 2017    maintain an adequate stock. Moreover, the high number
                          6
                                                         7
         the evaluation of parameters such as hypotension, presence   of requests and blood products prescribed, compared to
         of free fluid on ultrasound, clinical instability of the pelvic   the record of only 100 transfusion reactions, alerts us to
         ring, age, admission and mechanism of trauma, enabled   possible underreporting, suggesting improvements in the
         only 6% of 793 patients to be transfused in the emergency.  communication system with hospitals to highlight the
                                                               importance of hemovigilance.
         Although the sensitization rate is relatively low, there are still
         potentially fatal risks, especially in emergency transfusions
         performed without the completion of pretransfusion testing.   REFERENCES
         Alloimmunization causes several problems, from delay
                                                                                              o
         in obtaining compatible blood to hemolytic transfusion   1.  Brasil. Portaria de Consolidação n  5 de 28 de setembro
                 8
         reactions . The correct identification of these antibodies   de 2017. Consolidação das normas sobre as ações e os
         is fundamental to provide satisfactory transfusion support   serviços de saúde do Sistema Único de Saúde. Ministério
         and requires highly specialized immunohematology teams,   da Saúde [Internet]. 2017;926. Available from: http://
         especially when dealing with rare antibodies .        portalarquivos2.saude.gov.br/images/pdf/2018/marco/29/
                                               9
                                                               PRC-5-Portaria-de-Consolida----o-n---5--de-28-de-
         According to the guidelines recommended by PBM -      setembro-de-2017.pdf
         Patient Blood Management, optimizing the patient’s blood
         preoperatively by increasing hemoglobin/hematocrit levels,   2.  Murphy M BD. Recommendations on the Use of
         and proposing alternatives such as intraoperative blood   Group O Red Blood Cells. AABB Assoc Bull 19-02 2019.
         recovery and hemodilution, in addition to minimizing   2019;(D):1–12.
         hemostatic disorders, improve clinical outcomes by    3.  Pirenne F. Prevention of delayed hemolytic transfusion
         avoiding unnecessary exposure to blood components.    reaction. Transfus Clin Biol [Internet]. 2019;26(2):99–101.
         Strategies of this kind should be discussed and planned in   Available from: https://doi.org/10.1016/j.tracli.2019.02.007
         advance 8,10-11 .
                                                               4.  Gammon RR, Rosenbaum L, Cooke R, Friedman M,
          As cited earlier, about 3.2% of our patients had clinically
          significant alloantibodies undetectable on pretransfusion   Rockwood  L, Nichols  T,  et al.  Maintaining adequate
          testing. According to Chonat, 2019 , 30% of hemolytic   donations and a sustainable blood supply: Lessons learned.
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          transfusion reactions can occur under these conditions.   Transfusion. 2021;61(1):294–302.
          A relevant point observed in our results was the small   5.  Medvecz A, Bernard A, Hamilton C, Schuster KM,
          number of transfusion reactions reported, which denotes   Guillamondegui O, Davenport D. Transfusion rates in
          the occurrence of underreporting and suggests the need for   emergency general surgery: High but modifiable. Trauma
          improvements in the communication system with hospitals   Surg Acute Care Open. 2020;5(1):1–5.
          to highlight the importance of hemovigilance.
                                                               6.  Horst K, Lentzen R, Tonglet M, Mert Ü, Lichte P, Weber
          Another characteristic of our population was the age of the   CD, et al. Validation of the mTICCS Score as a Useful Tool
          patients. Although the median age was 54 years, 34% of   for the Early Prediction of a Massive Transfusion in Patients
          patients seen in the emergency modality were over 65 years   with a Traumatic Hemorrhage. J Clin Med. 2020;9(4):945.
          old, and anemia was the most common finding among the
          requests. According to Loftus, 2018 , anemia is common   7.  Alimohammadi H, Kianian Y, Zerepoosh F,
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          and morbid among the elderly, causing them to have lower   Derakhshanfar H, Alavi-Moghadam M, Hatamabadi H, et
          hemoglobin levels compared to younger patients, despite   al. Accuracy of emergency transfusion score in prediction
          receiving more transfusions. These data may reflect the   need for blood transfusion among multiple trauma patients:
          impact of nutritional deficiencies, multiple medications,   A cross-sectional study from Iran. Int J Crit Illn Inj Sci.
          and myelodysplasia in this population. Because they   2017;7(4):248–51.
          respond less to transfusion, exogenous administration of
          iron and erythropoietin may have therapeutic value in this   8.  Deepti Sachan; Aseem K. Tiwari; Ravi Dara; Dinesh
          group of patients.                                   Jothimani; Ilankumaran Kaliamoorthy; Srinivas Mettu
                                                               Reddy; Mohamed Rela. Patient blood management in a
                                                               patient with multiple red cell antibodies (anti-C, anti-e, and
         CONCLUSION                                            anti-K) undergoing liver transplant in South India: A team
                                                               approach. Asian J Transfus Sci. 2020;14((1)):74–8.
         Although the transfusion requests made in the emergency
         mode characterize the minority of cases, there is still a


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